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Vitamin E Supreme
Natural Mixed Tocopherols  DESCRIPTIONVitamin E Supreme by Nutrition Dynamics, Inc. contains 400 I.U. of 100% natural, unesterified vitamin E (d-alpha-tocopherol), plus other mixed tocopherols per softgel. No synthetic vitamin E is used. EVER!!! FUNCTIONS Vitamin E is the collective term for four fat-soluble, natural compounds with similar chemical structure; alpha-, beta-, gamma-, and delta-tocopherol. Of these, alpha-tocopherol has the highest nutritional activity. Eight structural isomers of alpha-tocopherol are possible, but only the d-alpha-tocopherol (RRR-alpha-tocopherol) occurs in nature. The other seven isomers have less nutritional activity, and are present only in synthetic vitamin E (dl-alpha-tocopherol) Douglas Laboratories’ vitamin E softgels contain only natural isomers of vitamin E, including d-alpha, d-beta, d-gamma, and d-delta tocopherols. Vitamin E is one of the body’s most important antioxidant nutrients. Antioxidants protect healthy cells from oxidative and free radical damage. Free radicals are unstable chemicals formed in the body during metabolism and from exposure to environmental sources, such as pollution and cigarette smoke. Free radicals are necessary for energy metabolism and immune function, but when an excessive number of free radicals are formed, they can attack healthy cells, especially cell membrane lipids and proteins. This, in turn, is thought to contribute to a number of degenerative diseases. Vitamin E is an especially valuable antioxidant in the cell membranes, where it prevents oxidation of unsaturated fatty acids by trapping free radicals. This helps stabilize and protect cell membranes, especially red blood cells and tissues sensitive to oxidation, such as the lungs, eyes, and arteries. Vitamin E also protects the liver and other tissues from the free-radical damage of toxicants, such as mercury, lead, ozone, nitrous oxide, carbon tetrachloride, benzene, cresol, and various drugs. Related to its antioxidant properties, vitamin E is important for normal immune function, and many studies show that it prevents lipid peroxidation of blood lipoproteins, such as LDL-cholesterol. Intestinal absorption of vitamin E is associated with fat absorption. Some dietary fat must be present for efficient vitamin E absorption to occur. Studies show that natural d‑alpha-tocopherol is more efficiently absorbed and has significantly higher bioavailability than synthetic dl-alpha-tocopherol. Once absorbed, vitamin E is transported into the circulatory system via chylomicrons, and then transferred to VLDL, LDL and HDL particles. Tissues slowly accumulate vitamin E from these plasma lipoproteins. Liver and adipose tissues have the highest concentrations, but muscle also accounts for a large proportion of vitamin E stores in the body.
INDICATIONS
Vitamin E
Supreme may
be a useful
dietary
supplement
for those
who wish to
increase
their daily
intake of
vitamin E in
its potent,
natural
form.
FORMULA
(#7059)
%U.S. RDA*
Each softgel
contains:
Vitamin E 400 I.U. 1,333 d-alpha-tocopherol 50%
d-beta-tocopherol
40%
d-gamma-tocopherol 5% d-delta-tocopherol 5%
*Percentage
of U.S.
Recommended
Daily
Allowance
(RDA) for
adults and
children
four or more
years of
age.
Other ingredients: soy bean oil, gelatin, glycerin, and purified water.
Contains no
yeast; corn;
wheat; sugar
or other
sweeteners;
artificial
flavors,
colors or
preservatives.
SUGGESTED USE
One softgel
daily with a
meal, or as
directed by
physician.
SIDE EFFECTS
None
reported.
The
safety of
oral vitamin
E has been
demonstrated
in doses as
high as
3,200 I.U.
per day.
PRECAUTIONS
Individuals
diagnosed
with vitamin
K deficiency
or on
anticoagulant
therapy
should
consult a
physician
before
taking high
doses of
vitamin E.
REFERENCES
Odeleye OE, Watson
RR. The potential
role of vitamin E in
the treatment of
immunologic
abnormalities during
acquired immune
deficiency syndrome.
Prog Food Nutr Sci
1991;15:1-19.
Paolisso G,
Gambardella A,
GI.U.gliano D, et
al. Chronic intake
of pharmacological
doses of vitamin E
might be useful in
the therapy of
elderly patients
with coronary heart
disease. Am J Clin
Nutr
1995;61:848-852.
Princen HMG, Van
Duyvenvoorde W,
Buytenhek R, et al.
Supplementation with
low doses of vitamin
E protects LDL from
lipid peroxidation
in men and women.
Arterioscler Thromb
1995;15:325-333.
Reiter RJ. Oxidative
processes and
antioxidative
defense mechanisms
in the aging brain.
FASEB J
1995;9:526-533.
Traber MG,
Ramakrishnan R,
Kayden HJ. Human
plasma vitamin E
kinetics demonstrate
rapid recycling of
plasma RRR-a-tocopherol.
Proc Natl Acad Sci
USA
1994;91:10005-10008.
Wang
Y, Watson RR.
Potential
therapeutics of
vitamin E
(tocopherol) in AIDS
and HIV. Drugs
1994;48:327-338.
Wang
Y, Huang DS, Liang
B, Watson RR.
Nutritional status
and immune responses
in mice with murine
AIDS are normalized
by vitamin E
supplementation. J
Nutr
1994;124:2024-2032.
Wang Y, Watson RR.
Is vitamin E
supplementation a
useful agent in AIDS
therapy? Prog Food
Nutr Sci
1993;17:351-375.
Winklhofer-Roob BM,
Ziouzenkova O, Puhl
H, et al. Impaired
resistance to
fibrosis:
improvement during
vitamin E
supplementation.
Free Radic Biol Med
1995;19:725-733.
Yau
TM, Weisel RD,
Mickle DAG, et al.
Vitamin E for
coronary bypass
operations: A
prospective,
double-blind,
randomized trial. J
Thorac Cardiovasc
Surg
1994;108:302-310.
These statements have not been evaluated by the Food and Drug Administration. .
This
product is not intended to diagnose,
treat, cure, or prevent any disease.
© 2008
Nutrition Dynamics, Inc. . All
Rights Reserved
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